MESA regularly reviews scientific literature related to the ingredients used in its products, and shares that review here. Our aim is to present relevant research responsibly and transparently.
All Research
How to read this library
01Evidence level describes the strength of the available published research.
02Formulation relevance describes how closely that research matches the ingredient's actual use in MESA products.
03Scientific literature provides context and does not automatically establish efficacy or clinical claims for MESA's finished products.
Scientific publications presented here concern individual ingredients or related preparations and should not be interpreted as clinical evidence for the finished MESA product unless explicitly stated.
STREPDOPS
Voice Care Lozenges
Scientific Literature
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Why is this ingredient used?
An ingredient may be included based on its established use, known properties, formulation purpose, or broader scientific interest even when clinical evidence for a specific outcome remains limited. The evidence level shown here describes the strength of the published evidence for the research question reviewed — it does not mean that the ingredient has no known properties or that its use in a formulation is scientifically meaningless.
What the evidence means
Evidence levels describe the strength and relevance of the available scientific literature. They should not be interpreted as a rating of the ingredient itself or as a direct clinical claim about MESA products.
Randomized Controlled Trial · 2006
Efficacy and tolerability of a spray with Salvia officinalis in the treatment of acute pharyngitis — a randomised, double-blind, placebo-controlled study with adaptive design and interim analysis
Hubbert M, Sievers H, Lehnfeld R, Kehrl W — European Journal of Medical Research
Whether a spray containing Salvia officinalis (sage) extract relieves the symptoms of acute pharyngitis (sore throat) compared to placebo.
Evidence Level
Moderate
Formulation Relevance
Related
The available research is relevant to the ingredient or a comparable application, but it still does not constitute clinical evidence for the finished MESA product.
Topical application of licorice for prevention of postoperative sore throat in adults: A systematic review and meta-analysis
Kuriyama A, Maeda H — Journal of Clinical Anesthesia
Whether a topical licorice gargle, used before surgery, prevents sore throat caused by tracheal intubation.
Evidence Level
Moderate
Formulation Relevance
Indirect
Indirect relevance means the available research is related to the ingredient or a similar use, but does not directly evaluate MESA's finished product or its exact formulation.
Toxicological Effects of Glycyrrhiza glabra (Licorice): A Review
Nazari S, Rameshrad M, Hosseinzadeh H — Phytotherapy Research
The toxicological and adverse-effect profile of licorice (Glycyrrhiza glabra) and its main constituent glycyrrhizin, across the available literature.
Evidence Level
Moderate
Formulation Relevance
Related
The available research is relevant to the ingredient or a comparable application, but it still does not constitute clinical evidence for the finished MESA product.
Zinc for prevention and treatment of the common cold
Nault D, Machingo TA, Shipper AG, Antiporta DA, Hamel C, Nourouzpour S, Konstantinidis M, Phillips E, Lipski EA, Wieland LS — Cochrane Database of Systematic Reviews
Whether zinc supplements prevent or shorten the common cold compared to placebo.
Evidence Level
Limited
Formulation Relevance
Related
The available research is relevant to the ingredient or a comparable application, but it still does not constitute clinical evidence for the finished MESA product.
Vitamin C for preventing and treating the common cold
Hemilä H, Chalker E — Cochrane Database of Systematic Reviews
Whether regular or therapeutic vitamin C supplementation prevents or shortens the common cold.
Evidence Level
Moderate
Formulation Relevance
Related
The available research is relevant to the ingredient or a comparable application, but it still does not constitute clinical evidence for the finished MESA product.